Yeruusaalem, 10 June, 2026 (TPS-IL) — Cilmi-baarayaal Israa'iili ayaa sameeyay nano-qaybo yaryar oo hoos u dhigay koritaanka burooyinka kansarka naasaha ee gardarrada ah ee moodooyinka horudhaca ah iyagoo aan wadan dawooyinka kiimoterabiga, unugyada difaaca jirka, ama dawo kale, sida lagu sheegay daraasad cusub oo ka timid Machadka Tignoolajiyada ee Technion Israel.
Soo-saarista, oo lagu daabacay joornaalka ACS Nano ee la qiimeeyay, ayaa soo jeedinaysa hab kale oo daawaynta kansarka: halkii laga gaarsiin lahaa dawo sun ah ama bartilmaameedka buurta, qaybahaasi waxay u muuqdaan inay ka shaqeeyaan iyagoo si fudud u beddelaya deegaanka difaaca ee buurta iyo xannibaya isdhexgalka waxyeelada leh ee caawiya kansarka inuu koro.
"Tani waa ka fiican daawaynta hadda jira ee leh unugyada difaaca ama kiimoterabiga, kuwaas oo leh waxyeelooyin badan," ayuu Professor Assaf Zinger, oo hoggaaminayay daraasadda, u sheegay The Press Service of Israel.
Daraasadda ayaa diiradda saartay kansarka naasaha ee "triple-negative," oo ah nooc ka mid ah cudurka oo loo arko mid si gaar ah u gardarra ah oo adag in la daaweeyo. Waxay si dhakhso ah u horumartaa oo aanay u jilicsanayn dhowr daawayn oo caadi ah sababtoo ah waxa ka maqan calaamadaha bayoolojiga ee ay bartilmaameedsadaan dawooyin badan oo hadda jira oo kansarka naasaha ah.
Cilmi-baarayaashu waxay naqshadeeyeen nano-qaybo loo yaqaan MPsomes si ay u faragaliyaan deegaanka micro-buurta, oo ah deegaanka bayoolojiga ee caawiya buurta inay noolaato, korodho, oo ka fogaato weerarrada nidaamka difaaca jirka.
Zinger ayaa sharaxay in unugyada kansarku ay khiyaami karaan unugyada difaaca jirka ee deegaankooda. Kuwaas waxaa ka mid ah macrophages, unugyada cad ee dhiigga kuwaas oo caadiyan caawiya inay ilaaliyaan jirka. Buuraha qaar, macrophages-ka waxaa loo soo jiitaa orbitka kansarka waxayna bilaabaan inay taageeraan koritaanka buurta halkii ay ka dagaallami lahaayeen.
Sida laga soo xigtay Zinger, MPsomes-ka waxay u shaqeeyaan sidii decoy bayooloji. Waxay u tartamaan meelaha isku xirka ee deegaanka buurta waxayna caawiyaan inay ka hortagaan unugyada difaaca jirka ee waxyeelada leh inay galaan buurta oo ay taageeraan horumarkeeda.
"Halkii si toos ah loo weerari lahaa unugyada kansarka iyadoo la isticmaalayo kiimoterabi ama unugyada difaaca, waxaan ognahay sida tan loo sameeyo iyadoo la isticmaalayo nano-qaybo aan wadan dawo oo isu ekaysiiya unugyada cad ee dhiigga," Zinger ayaa u sheegay TPS-IL. "Kadib waxay u tartamaan unugyada cad ee dhiigga meelaha isku xirka ee deegaanka buurta, kadibna unugyada cad ee dhiigga ee caawin lahaa kansarka si fudud uma gaaraan halkaas. Ilaa iyo inta aan ogahay, annagaa ah kuwa ugu horreeya ee caddeeya in qaybo madhan - taas oo macnaheedu yahay qaybo aan wadan dawo - ay yeelan karaan habdhaqan sidan."
Zinger ayaa intaa ku daray in nano-qaybaha ay ku urureen heerar sare agagaarka buurta waxayna hoos u dhigeen koritaanka buurta heer la mid ah daawaynta hadda jirta.
Daraasadda ayaa sidoo kale lagu ogaaday in nano-qaybaha ay beddeleen halabuurka unugyada difaaca jirka ee agagaarka buurta. Waxaa jiray unugyo difaac oo yar oo la xiriira taageerada buurta iyo unugyo badan oo la xiriira weerarkeeda.
"Dhanka haweenka jiirka, buurta si weyn ayay u yaraatay. Waxaan caddeynay in qaybaha madhan ay runtii ka hortagaan horumarka buurta," ayuu yiri Zinger.
Faa'iido kale oo suurtagal ah waa wax-soo-saarka. Sida laga soo xigtay Technion, habka ay sameeyeen cilmi-baarayaashu wuxuu soo saari karaa qiyaastii 20 millilitir oo nano-qaybo ah daqiiqadii, ama qiyaastii 1.2 litir saacadii.
Aasaaska qaybaha waxaa laga sameeyay inta badan agab ay Hay'adda Cuntada iyo Dawooyinka ee Mareykanka (FDA) u kala saartay "guud ahaan loo aqoonsaday inay ammaan yihiin," magac-siin taas oo caawin karta horumarka mustaqbalka haddii tignoolajiyada ay u sii gudubto imtixaanka dadka.
Zinger wuxuu xoogaa saaray in shaqadu ay weli ku jirto heerka horudhaca ah oo ilaa hadda kaliya lagu tijaabiyay moodooyinka jiirka. Waxaa loo baahan doonaa tijaabooyin caafimaad oo dadka ah ka hor inta aan habka loo tixgelin isticmaal caafimaad.
"Riyadaydu waa inaan tan gaarsiiyo rugta caafimaadka. Waqtiga la filayo waa ugu yaraan siddeed sano, waxaanan u dhawaan doonaa FDA laba sano gudahood," ayuu yiri Zinger. "Waxaan u maleynayaa in xilligan adag, helitaanka natiijooyin cilmiyeed oo iftiin faafin kara, inay tahay fariinteena, waana sababta aan u sameeyo waxa aan sameeyo.
