Yeruusaalem, 7 January, 2026 (TPS-IL) — Cilmi-baarayaal Israa’iili waxay ogaadeen in hurdadu ay bilawday boqolaal milyan oo sano ka hor xoolaha ugu horreeyay, oo ay ku jiraan jellyfish iyo sea anemones, isla markaana ujeeddadeedii ugu weynayd ay weli isku mid tahay tan iyo markaas: ilaalinta unugyada dareemaha ee dhaawaca. Daraasadda ayaa soo jeedinaysa in hagaajinta tayada hurdadu ay hoos u dhigi karto horumarka cudurrada neerfaha sida Alzheimer’s iyo Parkinson’s.
Hurdadu waa mid aad u baahsan xoolaha leh nidaam dareen, laakiin waxay la timid khataro daran. Inta ay hurdaan, xooluhu way yara ogyihiin hareerahooda, taas oo ka dhigaysa kuwo u nugul ugaadhsiga iyo carqaladaynta dhaqamada muhiimka ah sida quudinta. “Tani waxay had iyo jeer jahawareerisay saynisyahanada: maxay tahay sababta ay taran u ilaalinayso dhaqan khatar ah?” ayuu yiri Prof. Lior Appelbaum, oo ah madaxa Machadka Cilmi-nafsiga ee Bar-Ilan. Cilmi-baarista cusub ayaa soo jeedinaysa in jawaabtu ay ku jirto baahida muhiimka ah ee lagu dayactirayo neerfaha, faa’iido aad u muhiim ah oo ka miisaan culusayd khatarahaas tan iyo bilowgii.
Daraasad hore oo ka timid machadka Appelbaum ayaa muujisay in kalluunka zebrafish, neerfuhu ay urursadaan dhaawac DNA ah inta ay toosan yihiin isla markaana ay u baahan yihiin hurdada si ay u hagaajiyaan. Neerfuhu waa kuwo si gaar ah u nugul sababtoo ah, si ka duwan intooda badan unugyada, ma qaybsamaan mana si fudud loo beddeli karo.
Daraasadda hadda, oo ay hoggaaminayaan Dr. Raphael Aguillon iyo Dr. Amir Harduf, cilmi-baarayaashu waxay indha-indheeyeen hurdada laba nooc oo qadiimi ah: jellyfish diurnal oo firfircoon maalintii oo hurda habeenkii, iyo sea anemones crepuscular oo nasanaya subaxa. Iyagoo isticmaalaya fiidiyowga infrared iyo falanqaynta dhaqanka, cilmi-baarayaashu waxay ogaadeen in labada nooc ay hurdaan qiyaastii siddeed saacadood maalintii, oo la mid ah dadka.
Daraasadda ayaa muujisay in unugyada dareemaha ee labada nooc ay urursadaan dhaawac DNA ah inta ay toosan yihiin isla markaana ay hagaajiyaan inta ay hurdaan. Markii xoolaha la seexin waayay, waxay hurdeen muddo dheer ka dib – arrin loo yaqaan “sleep rebound”. Kordhinta dhaawaca DNA, ha ahaato iftiinka UV ama soo-gaadhista kiimikada, waxay kicisay hurdo dheeraad ah oo soo kabasho ah, halka kordhinta hurdada oo leh hormoonka melatonin ay hoos u dhigtay dhaawaca DNA.
“Soo-saaristaani waxay muujinaysaa in hurdada iyo caafimaadka unugyadu ay si adag isugu xiran yihiin,” ayay yiraahdeen cilmi-baarayaashu. “Dhaawaca ayaa kordhiya baahida hurdada, hurdada ayaa si firfircoon u hagaajisa.”
Daraasadda ayaa sidoo kale muujisay kala duwanaanshaha nidaamka hurdada. Jellyfish-ku waxay si weyn ugu tiirsan yihiin wareegga iftiinka-madow, halka sea anemones ay ku hagayaan saacad jirka ah oo gudaha ah. Inkasta oo ay jiraan kala duwanaanshiyahan, labada noocba waxay ku tiirsan yihiin hurdada si ay u ilaaliyaan caafimaadka neerfaha.
“Soo-saaristaani waxay soo jeedinaysaa in awoodda hurdada ee ilaalinta neerfaha ay tahay sifo qadiimi ah oo horeyba ugu jirta qaar ka mid ah xayawaanka ugu fudud ee leh nidaam dareen,” ayuu yiri Appelbaum. “Hurdadu waxay u badan tahay inay asal ahaan u soo baxday si loo siiyo neerfaha waqti gaar ah oo dayactir ah, shaqo aad u aasaasi ah oo sii jirta dhamaan boqortooyada xoolaha.”
Daraasadda ayaa leh saameyn cad oo ku saabsan dadka. Dhibaatooyinka hurdadu waxay la xiriiraan luminta xusuusta iyo khatarta sare ee cudurrada neerfaha sida Alzheimer’s iyo Parkinson’s, kuwaas oo laga yaabo inay ku lug leeyihiin dhaawac neerfaha oo socda. Cilmi-baarayaashu waxay arkaan suurtagalnimada horumarinta daawaynta kordhisa hababka dayactirka ee maskaxda, iyada oo la dhiirigelinayo hurdada soo kabashada ama iyada oo la barbar dhigayo saameynteeda ilaalinta.
“Hurdadu maaha oo kaliya muhiim u tahay barashada iyo xusuusta, laakiin sidoo kale ilaalinta neerfahayaga inay caafimaad qabaan,” ayuu yiri Appelbaum. “Drives-ka ilaalinta unugyada dareemaha ee aan ku aragno jellyfish iyo sea anemones ayaa laga yaabaa inay caawiso sharraxaadda sababta hurdadu ay muhiim ugu tahay dadka maanta. Soo-saaristaani waxay na siinaysaa sabab horumarineed oo aan si dhab ah u qaadano hurdada isla markaana xoojinayso doorkeeda caafimaadka maskaxda ee muddada dheer.”
Daraasadda waxaa lagu daabacay majaladda la qiimeeyay ee Nature Communications.
Mawduucyada La Xiriira
